The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 02, 2010

Filed:

Jul. 29, 2004
Applicant:

Atsushi Maruyama, Sagamihara, JP;

Inventor:

Atsushi Maruyama, Sagamihara, JP;

Assignee:

Japan Science and Technology Agency, Kawaguchi-Shi, Saitama, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); G01N 33/53 (2006.01); C12P 19/34 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The purpose of the present invention is to provide a substance having a several ten to several hundred-fold exchange reaction accelerating activity as compared with that of conventional copolymers. In particular, the invention provides a preparation for accelerating an exchange reaction between a nucleotide sequence at specific site of a double stranded DNA or RNA for its homologous nucleotide sequence, the preparation comprising a cationic polymer having a guanidine group-containing main chain and a hydrophilic functional groups as an active ingredient. Thus, a substance having a several ten to several hundred-fold exchange reaction accelerating activity as compared with that of conventional copolymers can be provided. With this substance, the nucleotide chain exchange can be performed at a lower temperature and/or a higher rate than in the prior art.


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