The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 02, 2010
Filed:
Mar. 20, 2003
Gary R. Klimpel, Santa Fe, TX (US);
David W. Niesel, Friendswood, TX (US);
Ashok Chopra, League City, TX (US);
Jian Sha, League City, TX (US);
Gary R. Klimpel, Santa Fe, TX (US);
David W. Niesel, Friendswood, TX (US);
Ashok Chopra, League City, TX (US);
Jian Sha, League City, TX (US);
The Board of Regents of the University of Texas System, Austin, TX (US);
Abstract
The present invention concerns the use of methods and compositions to prophylactically or therapeutically vaccinate a subject against a pathogen or disease. Embodiments of the invention include the production of an attenuated bacterium from the family Enterobacteriaceae with a non-functional lipoprotein for use as a vaccine or as a vaccine vector for delivering antigens to a subject to be vaccinated. In certain embodiments, a bacterium of the Enterobacteriaceae family lacking a wild type LP, for examplelacking a wild type LP, may be produced and used as a vaccine or vaccine vector.