The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 26, 2010
Filed:
Jun. 15, 2007
Andreas Lindenschmidt, Bad Soden, DE;
Holger Wagner, Biberach/Mettenberg, DE;
Jochen Beninga, Mainz, DE;
Sven Grueneberg, Kelkheim, DE;
Klaus-ulrich Weithmann, Hofheim, DE;
Andreas Lindenschmidt, Bad Soden, DE;
Holger Wagner, Biberach/Mettenberg, DE;
Jochen Beninga, Mainz, DE;
Sven Grueneberg, Kelkheim, DE;
Klaus-ulrich Weithmann, Hofheim, DE;
sanofi-aventis Deutschland GmbH, Frankfurt am Main, DE;
Abstract
The present invention relates to a novel compound of the formula I: and/or all stereoisomeric forms of the compound of the formula I and/or mixtures of these forms in any ratio, and/or a physiologically tolerated salt of the compound of the formula I, in which R1 to R5 and V1, V2 have the meanings stated in the claims and specification. The inventive compounds are suitable as inhibitors of metalloproteases, especially of ADAMTS proteases and TNF-α converting enzyme (TACE), and for the treatment of disorders such as but not limited to osteoarthrosis and rheumatoid arthritis.