The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 26, 2010
Filed:
Sep. 23, 2004
Hayley Binch, Encinitas, GB;
Simon Everitt, Oxfordshire, GB;
Francesca Mazzei, Wallingford, GB;
Daniel Robinson, Abingdon, GB;
Hayley Binch, Encinitas, GB;
Simon Everitt, Oxfordshire, GB;
Francesca Mazzei, Wallingford, GB;
Daniel Robinson, Abingdon, GB;
Vertex Pharmaceuticals Incorporated, Cambridge, MA (US);
Abstract
The present invention provides compounds of formula I: or a pharmaceutically acceptable derivative thereof, wherein A, B, Q, R, and Rare as described in the specification. These compounds are inhibitors of protein kinase, particularly inhibitors of AKT or PDK1 kinase, mammalian protein kinases involved in proliferative and neurodegenerative disorders. The invention also provides pharmaceutical compositions comprising the compounds of the invention, processes for preparing the compounds, and methods of utilizing those compositions in the treatment of various disorders.