The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 26, 2010

Filed:

Oct. 13, 2006
Applicants:

Raman K. Bakshi, Edison, NJ (US);

James P. Dellureficio, Millington, NJ (US);

Peter H. Dobbelaar, Morris Plains, NJ (US);

Liangqin Guo, Edison, NJ (US);

Shuwen He, Edison, NJ (US);

Qingmei Hong, Scotch Plains, NJ (US);

Ravi P. Nargund, East Brunswick, NJ (US);

Zhixiong YE, West Windsor, NJ (US);

Inventors:

Raman K. Bakshi, Edison, NJ (US);

James P. Dellureficio, Millington, NJ (US);

Peter H. Dobbelaar, Morris Plains, NJ (US);

Liangqin Guo, Edison, NJ (US);

Shuwen He, Edison, NJ (US);

Qingmei Hong, Scotch Plains, NJ (US);

Ravi P. Nargund, East Brunswick, NJ (US);

Zhixiong Ye, West Windsor, NJ (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/438 (2006.01); C07D 491/107 (2006.01);
U.S. Cl.
CPC ...
Abstract

Certain novel N-acylated spiropiperidine derivatives are ligands of the human melanocortin receptor(s) and, in particular, are selective ligands of the human melanocortin-4 receptor (MC-4R). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the modulation of MC-4R, such as obesity, diabetes, nicotine addiction, alcoholism, sexual dysfunction, including erectile dysfunction and female sexual dysfunction.


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