The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 26, 2010

Filed:

Jun. 01, 2005
Applicants:

Zhuyan Guo, Scotch Plains, NJ (US);

Peter Orth, New York, NY (US);

Zhaoning Zhu, Plainsboro, NJ (US);

Robert D. Mazzola, Stewartsville, NJ (US);

Tin-yau Chan, Edison, NJ (US);

Henry A. Vaccaro, South Plainfield, NJ (US);

Brian Mckittrick, New Vernon, NJ (US);

Joseph A. Kozlowski, Princeton, NJ (US);

Brian J. Lavey, Basking Ridge, NJ (US);

Guowei Zhou, Livingston, NJ (US);

Sunil Paliwal, Monroe Township, NJ (US);

Shing-chun Wong, Union, NJ (US);

Neng-yang Shih, Warren, NJ (US);

Pauline C. Ting, New Providence, NJ (US);

Kristin E. Rosner, Watertown, MA (US);

Gerald W. Shipps, Jr., Stoneham, MA (US);

M. Arshad Siddiqui, Newton, MA (US);

David B. Belanger, Cambridge, MA (US);

Chaoyang Dai, Acton, MA (US);

Dansu LI, Watertown, MA (US);

Vinay M. Girijavallabhan, Woburn, MA (US);

Janeta Popovici-muller, Waltham, MA (US);

Wensheng Yu, Edison, NJ (US);

Lianyun Zhao, Dorchester, MA (US);

Inventors:

Zhuyan Guo, Scotch Plains, NJ (US);

Peter Orth, New York, NY (US);

Zhaoning Zhu, Plainsboro, NJ (US);

Robert D. Mazzola, Stewartsville, NJ (US);

Tin-Yau Chan, Edison, NJ (US);

Henry A. Vaccaro, South Plainfield, NJ (US);

Brian McKittrick, New Vernon, NJ (US);

Joseph A. Kozlowski, Princeton, NJ (US);

Brian J. Lavey, Basking Ridge, NJ (US);

Guowei Zhou, Livingston, NJ (US);

Sunil Paliwal, Monroe Township, NJ (US);

Shing-Chun Wong, Union, NJ (US);

Neng-Yang Shih, Warren, NJ (US);

Pauline C. Ting, New Providence, NJ (US);

Kristin E. Rosner, Watertown, MA (US);

Gerald W. Shipps, Jr., Stoneham, MA (US);

M. Arshad Siddiqui, Newton, MA (US);

David B. Belanger, Cambridge, MA (US);

Chaoyang Dai, Acton, MA (US);

Dansu Li, Watertown, MA (US);

Vinay M. Girijavallabhan, Woburn, MA (US);

Janeta Popovici-Muller, Waltham, MA (US);

Wensheng Yu, Edison, NJ (US);

Lianyun Zhao, Dorchester, MA (US);

Assignee:

Schering Corporation, Kenilworth, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61K 31/506 (2006.01); A61K 31/4709 (2006.01); A61K 31/43 (2006.01); A61K 31/4245 (2006.01); C07D 413/00 (2006.01); C07D 241/36 (2006.01); C07D 471/00 (2006.01); C07D 295/00 (2006.01); C07D 471/02 (2006.01); C07D 401/00 (2006.01); C07D 513/00 (2006.01); C07D 277/22 (2006.01); C07D 277/62 (2006.01); C07D 263/30 (2006.01); C07D 261/06 (2006.01); C07D 235/00 (2006.01); C07D 209/04 (2006.01); C07D 207/00 (2006.01); C07D 205/00 (2006.01); C07D 409/00 (2006.01); C07D 307/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, TNF-α or combinations thereof.


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