The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 19, 2010

Filed:

Sep. 15, 2004
Applicants:

Christophe Echeverri, Dresden, DE;

Anthony Hyman, Dresden, DE;

Pierre Gönczy, Lausanne, CH;

Birte Sönnichsen, Dresden, DE;

Steven Jones, Vancouver, CA;

Andrew Walsh, Dresden, DE;

Liisa Koski, Dresden, DE;

Inventors:

Christophe Echeverri, Dresden, DE;

Anthony Hyman, Dresden, DE;

Pierre Gönczy, Lausanne, CH;

Birte Sönnichsen, Dresden, DE;

Steven Jones, Vancouver, CA;

Andrew Walsh, Dresden, DE;

Liisa Koski, Dresden, DE;

Assignee:

Cenix BioScience GmbH, Dresden, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to the significant functional role of severalgenes and of their corresponding gene products in cell cycle progression during cell division that could be identified by means of RNA-mediated interference (RNAi) and to the identification and isolation of functional orthologs of said genes including all biologically functional derivatives thereof. The invention further relates to the use of said genes and gene products (including said orthologs) in the development or isolation of anti-proliferative agents, particularly their use in appropriate screening assays, and their use for diagnosis and treatment of proliferative and other diseases. In particular, the invention relates to the use of small interfering RNAs derived from said genes for the treatment of proliferative diseases.


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