The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 12, 2010
Filed:
Dec. 01, 2006
Alexander Christian Comely, Barcelona, ES;
Marta Marfil Sánchez, Barcelona, ES;
Llorenç Rafecas Jané, Barcelona, ES;
Xavier Verdaguer Espaulella, Barcelona, ES;
Alexander Christian Comely, Barcelona, ES;
Marta Marfil Sánchez, Barcelona, ES;
Llorenç Rafecas Jané, Barcelona, ES;
Xavier Verdaguer Espaulella, Barcelona, ES;
Finorga SAS, Chasse Sur Rhone, FR;
Abstract
Process for the obtaining of 1-adamantane (tricycle[3.3.1.1 (3,7)]decane) derivatives, or of a pharmaceutically acceptable salt thereof, based on a carboxylation reaction, via metallation, of a precursor compound with an adequate leaving group. It also comprises the preparation of the precursor compound by means of a selective coupling of the corresponding boron, magnesium or zinc derivative with the corresponding disubstitute aromatic derivative. It is especially useful for the obtaining of Adapalene at industrial scale with good yield and high purity.