The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7645864 B1

PDF
Full Text
Expired
Date of Patent:
Jan. 12, 2010

Filed:

Oct. 12, 2001
Applicants:

Akira Hiraide, Tokyo, JP;

Kaichiro Koyama, Tokyo, JP;

Hitoshi Shimizu, Tokyo, JP;

Kaname Tsuzaki, Tokyo, JP;

Inventors:

Akira Hiraide, Tokyo, JP;

Kaichiro Koyama, Tokyo, JP;

Hitoshi Shimizu, Tokyo, JP;

Kaname Tsuzaki, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 17/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides an E-type crystal of N-demethyl-N-isopropyl-12-methoxy-11-oxo-8,9-anhydroerythromycin A-6,9-hemiacetal fumarate having strong diffraction peaks at diffraction angles (2θ) of 5.6° and 10.4° as measured by powder X-ray diffractometry, which is prepared by treating a C-type crystal of the compound in a mixed solvent of ethyl acetate and water at 20° C. to 40° C., and a D-type crystal prepared via the E-type crystal. These crystals have a reduced content of residual solvent and high suitability for formulation.


Find Patent Forward Citations

Hiraide, Akira. (2010). Erythromycin derivative having novel crystal structures and processes for their production (U.S. Patent No. 7645864). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7645864

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