The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 12, 2010

Filed:

Aug. 20, 2004
Applicants:

Hiroyuki Abe, Osaka, JP;

Jonathan Houze, San Mateo, CA (US);

Hisashi Kawasaki, Osaka, JP;

Frank Kayser, San Francisco, CA (US);

Rajiv Sharma, Fremont, CA (US);

Samuel Sperry, San Diego, CA (US);

Inventors:

Hiroyuki Abe, Osaka, JP;

Jonathan Houze, San Mateo, CA (US);

Hisashi Kawasaki, Osaka, JP;

Frank Kayser, San Francisco, CA (US);

Rajiv Sharma, Fremont, CA (US);

Samuel Sperry, San Diego, CA (US);

Assignees:

Amgen Inc., Thousand Oaks, CA (US);

Japan Tobacco, Inc., Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/44 (2006.01); A61K 31/19 (2006.01); C07D 213/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds, compositions and methods that are useful for the treatment of metabolic disorders, inflammatory diseases and cancer are provided herein. In particular, the invention provides compounds which modulate the expression and/or function of proteins involved in lipid metabolism, inflammation and cell proliferation. The subject compounds are linked biaryl compounds.


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