The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 12, 2010

Filed:

Feb. 17, 2005
Applicants:

Toshiyuki Takahashi, Tsukuba, JP;

Akio Kanatani, Ushiku, JP;

Shigeru Tokita, Tsukuba, JP;

Ryo Yoshimoto, Tsukuba, JP;

Inventors:

Toshiyuki Takahashi, Tsukuba, JP;

Akio Kanatani, Ushiku, JP;

Shigeru Tokita, Tsukuba, JP;

Ryo Yoshimoto, Tsukuba, JP;

Assignee:
Attorneys:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/5025 (2006.01); A61K 31/53 (2006.01); A61P 3/04 (2006.01); A61P 3/10 (2006.01); A61P 9/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides a compound or its pharmaceutically-acceptable salt of formula wherein Ais a hydrogen, etc.; j and k are 0 or 1;is a double bond, etc.;is a double bond, etc.;one of Wand Wis E—O—W, etc., and the other is a hydrogen atom, etc.; E is a divalent group derived from a benzene ring, etc., by removing two hydrogen atoms therefrom; W is a group of formula (II-1): which has a histamine-H3 receptor antagonistic effect or a histamine-H3 receptor inverse-agonistic effect and is useful for prevention or remedy of metabolic system diseases, circulatory system diseases or nervous system diseases.


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