The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 12, 2010
Filed:
Mar. 17, 2006
Yuk-ming Dennis Lo, Kowloon, HK;
Rossa Wai Kwun Chiu, Tai Po, HK;
BO Yin Tsui, Kowloon, HK;
Chunming Ding, Shatin, HK;
Charles Cantor, Del Mar, CA (US);
Yuk-Ming Dennis Lo, Kowloon, HK;
Rossa Wai Kwun Chiu, Tai Po, HK;
Bo Yin Tsui, Kowloon, HK;
Chunming Ding, Shatin, HK;
Charles Cantor, Del Mar, CA (US);
The Chinese University of Hong Kong, Shantin, N.T., HK;
Abstract
The non-invasive detection of fetal chromosomal aneuploidies is demonstrated. Alleles of fetal RNA-SNPs present in a biological sample (e.g. maternal blood) containing fetal RNA are detected and quantified in order to determine the ratio of the alleles. This ratio is compared to a standard control consisting of euploid fetuses. Deviation of allele ratio indicates the presence of chromosomal aneuploidy.