The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 12, 2010
Filed:
Dec. 29, 2005
Tae Hyoung Yoo, Seoul, KR;
Moo Young Song, Suwon-si, KR;
Chang Seok Kim, Suwon-si, KR;
Sang Koo Park, Yongin-si, KR;
Kang IN NA, Yongin-si, KR;
Byung Kyu Lee, Gunpo-si, KR;
Heui IL Kang, Gunpo-si, KR;
Tae Hyoung Yoo, Seoul, KR;
Moo Young Song, Suwon-si, KR;
Chang Seok Kim, Suwon-si, KR;
Sang Koo Park, Yongin-si, KR;
Kang In Na, Yongin-si, KR;
Byung Kyu Lee, Gunpo-si, KR;
Heui Il Kang, Gunpo-si, KR;
Yuhan Corporation, Seoul, KR;
Abstract
Humanized antibodies specifically binding to hTNF-α are prepared from a mouse monoclonal antibody by the CDR (complementarity determining region) grafting method, and they show an antigen binding affinity similar to the original mouse monoclonal antibody and significantly low immunogenicity. Therefore, the humanized antibodies can be effectively used for treating a hTNF-α-related disease such as rheumatoid arthritis, Crohn's disease, psoriatic arthritis, psoriasis, septicemia, asthma, Wegener's granulomatosis, inflammation, and ankylosing spondylitis.