The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 12, 2010

Filed:

Aug. 04, 2003
Applicants:

Ron L. Hale, Woodside, CA (US);

Peter M. Lloyd, Walnut Creek, CA (US);

Amy LU, Los Altos, CA (US);

Daniel J. Myers, Mountain View, CA (US);

Reynaldo J. Quintana, Redwood City, CA (US);

Joshua D. Rabinowitz, Mountain View, CA (US);

Dennis W. Solas, San Francisco, CA (US);

Soonho Song, Palo Alto, CA (US);

Curtis Tom, San Mateo, CA (US);

Martin J. Wensley, San Francisco, CA (US);

Inventors:

Ron L. Hale, Woodside, CA (US);

Peter M. Lloyd, Walnut Creek, CA (US);

Amy Lu, Los Altos, CA (US);

Daniel J. Myers, Mountain View, CA (US);

Reynaldo J. Quintana, Redwood City, CA (US);

Joshua D. Rabinowitz, Mountain View, CA (US);

Dennis W. Solas, San Francisco, CA (US);

Soonho Song, Palo Alto, CA (US);

Curtis Tom, San Mateo, CA (US);

Martin J. Wensley, San Francisco, CA (US);

Assignee:

Alexza Pharmaceuticals, Inc., Mountain View, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/12 (2006.01); A61K 9/14 (2006.01); A61M 15/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

A device, method, and system for producing a condensation aerosol are disclosed. The device includes a chamber having an upstream opening and a downstream opening which allow gas to flow through the chamber, and a heat-conductive substrate located at a position between the upstream and downstream openings. Formed on the substrate is a drug composition film containing a therapeutically effective dose of a drug when the drug is administered in aerosol form. A heat source in the device is operable to supply heat to the substrate to produce a substrate temperature greater than 300° C., and to substantially volatilize the drug composition film from the substrate in a period of 2 seconds or less. The device produces an aerosol containing less than about 10% by weight drug composition degradation products and at least 50% of the drug composition of said film.


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