The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 05, 2010
Filed:
Feb. 28, 2006
Sameer Urgaonkar, Cambridge, MA (US);
John G. Verkade, Ames, IA (US);
Sameer Urgaonkar, Cambridge, MA (US);
John G. Verkade, Ames, IA (US);
Iowa State University Research Foundation, Inc., Ames, IA (US);
Abstract
A method is provided to couple an aryl halide to an alkyne comprising reacting a compound of the formula ArX, wherein Ar is a substituted or unsubstituted aryl group and X is I or Br, with a compound of the formula HC≡C—Rwherein Ris a substituted or unsubstituted organic group, in the presence of an effective amount of a phosphine-free, oxime-free palladium catalyst; (C-C)alkyl N(OAc) or an alkali metal carbonate, to yield a compound of the formula Ar—C≡C—R, wherein the reaction is carried out in the absence of an organic amine or copper(I).