The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 05, 2010
Filed:
May. 19, 2003
Simon Feldbæk Nielsen, Herlev, DK;
Kristian Schønning, Hellerup, DK;
Hasse Kromann, Copenhagen V, DK;
Thomas Boesen, Copenhagen Ø, DK;
Mogens Larsen, Smørum, DK;
Simon Feldbæk Nielsen, Herlev, DK;
Kristian Schønning, Hellerup, DK;
Hasse Kromann, Copenhagen V, DK;
Thomas Boesen, Copenhagen Ø, DK;
Mogens Larsen, Smørum, DK;
Lica Pharmaceuticals A/S, Copenhagen, DK;
Abstract
The invention provides novel diamino-functionalized chalcone derivatives and analogues thereof. Use of the compounds, or compositions comprising them, as pharmaceutically active agents, in particular against bacterial and parasitic infections, is also disclosed. The invention further relates to a method for detecting inhibitory effects against e.g., bacteria, parasites, fungi, and helminths. The chalcones of the invention carry amino substituents and exhibit enhanced biological effects combined with improved metabolic and physicochemical properties, making the compounds useful as drug substances, in particular as antiparasitic and bacteriostatic agents.