The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 05, 2010

Filed:

Oct. 05, 2006
Applicants:

Rajinder Singh, Belmont, CA (US);

Ankush Argade, Foster City, CA (US);

Donald Payan, Hillsborough, CA (US);

Susan Molineaux, San Mateo, CA (US);

Sacha J. Holland, San Francisco, CA (US);

Jeffrey Clough, Redwood City, CA (US);

Holger Keim, Menlo Park, CA (US);

Somasekhar Bhamidipati, Foster City, CA (US);

Catherine Sylvain, Burlingame, CA (US);

Hui LI, Millbrae, CA (US);

Alexander B. Rossi, San Francisco, CA (US);

Inventors:

Rajinder Singh, Belmont, CA (US);

Ankush Argade, Foster City, CA (US);

Donald Payan, Hillsborough, CA (US);

Susan Molineaux, San Mateo, CA (US);

Sacha J. Holland, San Francisco, CA (US);

Jeffrey Clough, Redwood City, CA (US);

Holger Keim, Menlo Park, CA (US);

Somasekhar Bhamidipati, Foster City, CA (US);

Catherine Sylvain, Burlingame, CA (US);

Hui Li, Millbrae, CA (US);

Alexander B. Rossi, San Francisco, CA (US);

Assignee:

Rogel Pharmaceuticals, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 239/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides 2,4-pyrimidinediamine compounds that inhibit the IgE and/or IgG receptor signaling cascades that lead to the release of chemical mediators, intermediates and methods of synthesizing the compounds and methods of using the compounds in a variety of contexts, including in the treatment and prevention of diseases characterized by, caused by or associated with the release of chemical mediators via degranulation and other processes effected by activation of the IgE and/or IgG receptor signaling cascades.


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