The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 05, 2010

Filed:

Jun. 29, 2004
Applicants:

Michael J. Yaszemski, Rochester, MN (US);

Bradford L. Currier, Rochester, MN (US);

Esmaiel Jabbari, Columbia, SC (US);

Lichun LU, Rochester, MN (US);

Inventors:

Michael J. Yaszemski, Rochester, MN (US);

Bradford L. Currier, Rochester, MN (US);

Esmaiel Jabbari, Columbia, SC (US);

Lichun Lu, Rochester, MN (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08F 297/02 (2006.01); C08F 297/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

A composition is disclosed which comprises (i) a macromer prepared by reacting an unsaturated diacid having a carbon-carbon double bond and a saturated diacid, and (ii) a bioactive ceramic grafted to the macromer. In one embodiment, the unsaturated diacid having a carbon-carbon double bond is fumaric acid, the saturated diacid is compatible with fumaric acid and poly(propylene fumarate) such as succinic acid, glutaric acid, adipic acid, pimelic acid, suberic acid, azelaic acid, sebacic acid and mixtures thereof, and the bioactive ceramic is hydroxyapatite. In another embodiment, hydroxyapatite is grafted with a biodegradable and crosslinkable macromer comprising silane units alternating with furnarate and adipate units.


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