The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 29, 2009
Filed:
Feb. 03, 2005
Applicants:
Josef Hajicek, Praha, CZ;
Marketa Slavikova, Libcice nad Vltavou, CZ;
Inventors:
Josef Hajicek, Praha, CZ;
Marketa Slavikova, Libcice nad Vltavou, CZ;
Assignee:
Zentiva, k.s., Praha, CZ;
Primary Examiner:
Int. Cl.
CPC ...
C07C 311/39 (2006.01);
U.S. Cl.
CPC ...
Abstract
A method of preparation of (R)-(−)-5-(2-aminopropyl)-2-methoxybenzenesulfonamide of formula I and its use for production tamsulosin. A protective group is introduced to N-[(1R)-2(4-methoxyphenyl)-1-methylethyl]-N-[(1R)-1-phenylethyl)]amine and the resulting amide of formula IX is chlorosulfonated and the resulting sulfochloride is converted to a sulfonamide of formula X, from which the compound of formula I is obtained by hydrogenation.