The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 29, 2009

Filed:

Apr. 15, 2003
Applicants:

Marie-agnès Lassoie, Braine-le-Château, BE;

Laurent Knerr, Göteborg, SE;

Thierry Demaude, Saint-Ghislain, BE;

Françoise DE Laveleye-defais, Brussels, BE;

Thierry Kogej, Göteborg, SE;

Luc Quere, Dampicourt, BE;

Sylvain Routier, Tigy, FR;

Gerald Guillaumet, St-Jean-le-Blanc, FR;

Inventors:

Marie-Agnès Lassoie, Braine-le-Château, BE;

Laurent Knerr, Göteborg, SE;

Thierry Demaude, Saint-Ghislain, BE;

Françoise De Laveleye-Defais, Brussels, BE;

Thierry Kogej, Göteborg, SE;

Luc Quere, Dampicourt, BE;

Sylvain Routier, Tigy, FR;

Gerald Guillaumet, St-Jean-le-Blanc, FR;

Assignee:

UCB Pharma S.A., Brussels, BE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/38 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention concerns 2,6-quinolinyl and 2,6-naphthyl derivatives of formula (I), processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals for the treatment of VLA-4 dependent inflammatory diseases such as for example asthma, allergic rhinitis, sinusitis, conjunctivitis, food allergy, psoriasis, urticaria, pruritus, eczema, rheumatoid arthritis, inflammatory bowel disease, multiple sclerosis and atherosclerosis. Formula (I): wherein X is N or CH.


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