The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 29, 2009
Filed:
Dec. 22, 2006
Serge Van Calenbergh, De Pinte, BE;
Timothy Haemers, Mariakerke, BE;
Vincent Devreux, Waregem, BE;
Hassan Jomaa, Giessen, DE;
Jochen Wiesner, Giessen, DE;
Serge Van Calenbergh, De Pinte, BE;
Timothy Haemers, Mariakerke, BE;
Vincent Devreux, Waregem, BE;
Hassan Jomaa, Giessen, DE;
Jochen Wiesner, Giessen, DE;
Universiteit Gent, , BE;
Abstract
The present invention relates to novel phosphonic acid compounds having the structural formula (I): wherein: (a) R is a group of 1 to 5 substituents independently selected from the group consisting of fluoro, chloro, bromo, Calkoxy, Calkyl, hydroxy, formyl, trifluoromethoxy, phenyl, heterocyclic, heterocyclic-substituted methyl, aminomethyl, hydroxy methyl, bromomethyl, sulfonyl chloride, acetyl chloride, nitroso and cyano, (b) Ris selected from the group consisting of hydrogen, Calkyl, Ccycloalkyl, aryl, arylalkyl and heterocyclic, and (c) Ris selected from the group consisting of hydroxy and hydroxy-protecting groups, and stereoisomer, solvates and salts thereof. These compounds are useful as anti-infectious and anti-parasitic agents, in particular anti-malaria agents.