The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 29, 2009

Filed:

Jul. 12, 2006
Applicants:

Mirella Lazarov, Hayward, CA (US);

Catherine Middleton-hardie, Hayward, CA (US);

David Rosen, Hayward, CA (US);

Inventors:

Mirella Lazarov, Hayward, CA (US);

Catherine Middleton-Hardie, Hayward, CA (US);

David Rosen, Hayward, CA (US);

Assignee:

Acologix, Inc., Hayward, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/18 (2006.01); C07K 14/51 (2006.01); A61F 2/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Formulations and methods to promote biological processes to form or regenerate new hard tissues such as bones, cartilage, and/or dental tissues are disclosed. The formulation comprising two proteins is administered to enhance biological activities of a hard tissue growth and differentiation factor characterized by specific and selective upregulation and/or extension of the retention time of the intracellular enzymes and signaling molecules that play important roles to proliferate, differentiate, maturate, and/or mineralize the hard tissue forming cells.


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