The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 29, 2009

Filed:

Jul. 07, 2004
Applicants:

J. Christopher Anderson, San Francisco, CA (US);

Ning Wu, Brookline, MA (US);

Stephen Santoro, Cambridge, MA (US);

Peter G. Schultz, La Jolla, CA (US);

Inventors:

J. Christopher Anderson, San Francisco, CA (US);

Ning Wu, Brookline, MA (US);

Stephen Santoro, Cambridge, MA (US);

Peter G. Schultz, La Jolla, CA (US);

Assignee:

The Scripps Research Institute, La Jolla, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 21/06 (2006.01); C07H 21/04 (2006.01); C12N 9/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal lysyl-tRNAs, orthogonal lysyl-aminoacyl-tRNA synthetases, and orthogonal pairs of lysyl-tRNAs/synthetases, which incorporate homoglutamines into proteins are provided in response to a four base codon. Methods for identifying these orthogonal pairs are also provided along with methods of producing proteins with homoglutamines using these orthogonal pairs.


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