The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 22, 2009
Filed:
Dec. 29, 2004
David C. Boisvert, El Cerrito, CA (US);
Malinda Longphre, Oakland, CA (US);
Teresa M. Wong, Lafayette, CA (US);
Sydney M. Zaremba, Alameda, CA (US);
David C. Boisvert, El Cerrito, CA (US);
Malinda Longphre, Oakland, CA (US);
Teresa M. Wong, Lafayette, CA (US);
Sydney M. Zaremba, Alameda, CA (US);
Aerovance, Inc., Berkeley, CA (US);
Abstract
Chimeric polypeptide antagonists that include an interleukin-4 (IL-4) mutein linked to an interleukin-9 (IL-9) mutein are provided, as are polynucleotides encoding the IL-4 and IL-9 chimeric mutein antagonists. Also provided are methods of using the chimeric mutein antagonists and encoding polypeptides to reduce or inhibit the responsiveness of a cell to a cytokine such as IL-4, IL-9 and/or interleukin-13. Methods using the compositions to treat disorders such as pulmonary disorders (e.g., asthma) also are provided.