The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 22, 2009

Filed:

Feb. 21, 2007
Applicants:

Simon A. Burkitt, Kirkby-in-Ashfield, GB;

Mario G. Cardozo, San Francisco, CA (US);

Timothy D. Cushing, Pacifica, CA (US);

Michael R. Degraffenreid, San Francisco, CA (US);

Christopher N. Farthing, Macclesfield, GB;

Xiaolin Hao, Foster City, CA (US);

Juan C. Jaen, Burlingame, CA (US);

Xian Yun Jiao, San Mateo, CA (US);

David J. Kopecky, San Francisco, CA (US);

Marc Labelle, Burlingame, CA (US);

Sarah E. Lively, Congleton, GB;

Dustin L. Mcminn, Pacifica, CA (US);

Sven P. Rasmussen, Congleton, GB;

Youngsook Shin, San Mateo, CA (US);

Marie-louise Smith, Half Moon Bay, CA (US);

Andrew Smith, Macclesfield, GB;

Inventors:

Simon A. Burkitt, Kirkby-in-Ashfield, GB;

Mario G. Cardozo, San Francisco, CA (US);

Timothy D. Cushing, Pacifica, CA (US);

Michael R. DeGraffenreid, San Francisco, CA (US);

Christopher N. Farthing, Macclesfield, GB;

Xiaolin Hao, Foster City, CA (US);

Juan C. Jaen, Burlingame, CA (US);

Xian Yun Jiao, San Mateo, CA (US);

David J. Kopecky, San Francisco, CA (US);

Marc Labelle, Burlingame, CA (US);

Sarah E. Lively, Congleton, GB;

Dustin L. McMinn, Pacifica, CA (US);

Sven P. Rasmussen, Congleton, GB;

Youngsook Shin, San Mateo, CA (US);

Marie-Louise Smith, Half Moon Bay, CA (US);

Andrew Smith, Macclesfield, GB;

Assignee:

Amgen Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/5377 (2006.01); A61K 31/4365 (2006.01); C07D 413/14 (2006.01); C07D 495/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds, compositions and methods that are useful in the treatment of inflammatory, immunoregulatory, metabolic, infectious and cell proliferative diseases or conditions are provided herein. In particular, the invention provides compounds which modulate the expression and/or function of proteins involved in inflammation, metabolism, infection and cell proliferation. The subject compounds contain a fused heterobicyclic ring.


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