The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 22, 2009
Filed:
Oct. 03, 2006
Raymond F. Schinazi, Decatur, GA (US);
Jennifer L. Hammond, Pittsburgh, PA (US);
John W. Mellors, Pittsburgh, PA (US);
Dennis C. Liotta, McDonough, GA (US);
Raymond F. Schinazi, Decatur, GA (US);
Jennifer L. Hammond, Pittsburgh, PA (US);
John W. Mellors, Pittsburgh, PA (US);
Dennis C. Liotta, McDonough, GA (US);
Emory University, Atlanta, GA (US);
Abstract
The present invention discloses a method for treating HIV that includes administering β-D-D4FC or its pharmaceutically acceptable salt or prodrug to a human in need of therapy in combination or alternation with a drug that induces a mutation in HIV-1 at a location other than the 70(K to N), 90 or the 172 codons of the reverse transcriptase region. Also disclosed is a method for using β-D-D4FC as 'salvage therapy' to patients which exhibit drug resistance to other anti-HIV agents. β-D-D4FC can be used generally as salvage therapy for any patient which exhibits resistance to a drug that induces a mutation at other than the 70(K to N), 90 or the 172 codons.