The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 15, 2009
Filed:
Jun. 25, 2004
Yoshiji Takemoto, Otsu, JP;
Yoshiji Takemoto, Otsu, JP;
Sumitomo Chemical Company, Limited, Tokyo, JP;
Abstract
The present invention relates to a production method of asymmetric compound (IV) which includes conjugately adding nucleophilic reagent (III) to compound (II) in the presence of asymmetric urea compound (I). The present invention provides a non-metallic asymmetric catalyst capable of realizing a highly stereoselective asymmetric conjugate addition reaction in a high yield, and an advantageous production method of an asymmetric compound by an asymmetric conjugate addition reaction using the asymmetric catalyst. wherein X is an oxygen atom or a sulfur atom; C*, C** and C*** are asymmetric carbons; R, R, R, R, R, Rand Rare each a lower alkyl group optionally having substituent(s) and the like, or Rand Rand the like in combination optionally form a homocyclic ring optionally having substituent(s) and the like; Ris an aryl group optionally having substituent(s) and the like; Rand Rare each a hydrogen atom and the like; Nu is —CR(COR)(COR) wherein R, Rand Rare each a lower alkyl group optionally having substituent(s) and the like, and the like; and EWG is an electron withdrawing group.