The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 15, 2009
Filed:
Mar. 26, 2004
Thomas Wisniewski, Staten Island, NY (US);
Marcin Sadowski, Bronx, NY (US);
Einar M. Sigurdsson, New York, NY (US);
Blas Frangione, New York, NY (US);
Thomas Wisniewski, Staten Island, NY (US);
Marcin Sadowski, Bronx, NY (US);
Einar M. Sigurdsson, New York, NY (US);
Blas Frangione, New York, NY (US);
New York University, New York, NY (US);
Abstract
The present invention is directed to a method of preventing or treating Alzheimer's Disease or of inhibiting accumulation of amyloid-β deposits in a subject by administering to the subject an agent which inhibits interaction between amyloid-β and proteins which chaperone amyloid-β under conditions effective to prevent or treat Alzheimer's Disease in the subject or to inhibit accumulation of amyloid-β deposits in the subject's brain, respectively. Another embodiment of the present invention relates to a method of inhibiting interaction between apolipoprotein E and amyloid-β by administering an agent which blocks interaction of apolipoprotein E and amyloid-β under conditions effect to block such interaction.