The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 15, 2009

Filed:

Apr. 25, 2005
Applicants:

Yasuo Ochi, Mishima-gun, JP;

Makoto Tanaka, Mishima-gun, JP;

Naoki Kawada, Mishima-gun, JP;

Hiroyuki Yamada, Mishima-gun, JP;

Hiroshi Mori, Mishima-gun, JP;

Ryouji Kayasuga, Mishima-gun, JP;

Inventors:

Yasuo Ochi, Mishima-gun, JP;

Makoto Tanaka, Mishima-gun, JP;

Naoki Kawada, Mishima-gun, JP;

Hiroyuki Yamada, Mishima-gun, JP;

Hiroshi Mori, Mishima-gun, JP;

Ryouji Kayasuga, Mishima-gun, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/70 (2006.01); A61K 31/425 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to an agent for increasing BMD characterized by use of a cathepsin K inhibitor as a bone resorption inhibitor in combination with a type of PTH as a bone formation stimulator. This agent for increasing BMD is useful for the treatment of osteoporosis, bone fracture, arthritis, rheumatoid arthritis, osteoarthritis, hypercalcemia, osteometastasis of carcinoma, periodontal disease, bone Paget's disease and other bone metabolic diseases. For example, as the cathepsin K inhibitor, there can be mentioned a compound of formula (W) and a salt thereof, etc.


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