The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 15, 2009
Filed:
Mar. 17, 2004
Harald Gröger, Hanau, DE;
Claudia Rollmann, Alzenau, DE;
Hendrik Hüsken, Haltern am See, DE;
Helge Werner, Bruchköbel, DE;
Francoise Chamouleau, Hanau, DE;
Chad Hagedorn, Bellbrook, OH (US);
Karlheinz Drauz, Freigericht, DE;
Werner Hummel, Titz, DE;
Harald Gröger, Hanau, DE;
Claudia Rollmann, Alzenau, DE;
Hendrik Hüsken, Haltern am See, DE;
Helge Werner, Bruchköbel, DE;
Francoise Chamouleau, Hanau, DE;
Chad Hagedorn, Bellbrook, OH (US);
Karlheinz Drauz, Freigericht, DE;
Werner Hummel, Titz, DE;
Evonik Degussa GmbH, Essen, DE;
Abstract
The present application relates to a reaction system in which chemically valuable compounds can be obtained in high enantiomer concentrations with the aid of a coupled enzymatically operating transformation process. The coupled enzymatic reaction system comprises a cofactor-dependent enzymatic transformation of an organic compound and an enzymatic regeneration of the cofactor, wherein the reaction system operates in aqueous solution with an amount of substrate above the solubility limit thereof. In the preferred embodiments, an alcohol dehydrogenase is the cofactor-dependent enzyme, and the regeneration of the cofactor (e.g. NADH or NADPH) is acheved by means of formate dehydrogenase.