The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 15, 2009
Filed:
Jul. 18, 2006
Jianmin Fang, Palo Alto, CA (US);
Karin Jooss, Bellevue, WA (US);
Andrew Simmons, San Mateo, CA (US);
Debbie Farson, San Francisco, CA (US);
Jing Jing Qian, Foster City, CA (US);
Jianmin Fang, Palo Alto, CA (US);
Karin Jooss, Bellevue, WA (US);
Andrew Simmons, San Mateo, CA (US);
Debbie Farson, San Francisco, CA (US);
Jing Jing Qian, Foster City, CA (US);
BioSante Pharmaceuticals, Inc., Lincolnshire, IL (US);
Abstract
Lentivector constructs for expression of recombinant proteins, polypeptides or fragments thereof and methods of making the same are described. The lentivectors typically have a self-processing cleavage sequence between a first and second protein or polypeptide coding sequence allowing for expression of a functional protein or polypeptide under operative control of a single promoter and may further include an additional proteolytic cleavage sequence which provides a means to remove the self-processing cleavage sequence from the expressed protein or polypeptide. The vector constructs find utility in methods relating to enhanced production of biologically active proteins, such as immunoglobulins or fragments thereof in vitro and in vivo.