The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 08, 2009
Filed:
Sep. 19, 2001
Rajiv Chopra, Belmont, MA (US);
Kristine Svenson, Andover, MA (US);
Bethany Annis Freeman, Belmont, MA (US);
Tatos N. Akopian, West Roxbury, MA (US);
Jonathan Bard, Doylestown, PA (US);
Mark Lloyd Stahl, Lexington, MA (US);
William S. Somers, Cambridge, MA (US);
Rajiv Chopra, Belmont, MA (US);
Kristine Svenson, Andover, MA (US);
Bethany Annis Freeman, Belmont, MA (US);
Tatos N. Akopian, West Roxbury, MA (US);
Jonathan Bard, Doylestown, PA (US);
Mark Lloyd Stahl, Lexington, MA (US);
William S. Somers, Cambridge, MA (US);
American Home Products Corporation, Madison, NJ (US);
Abstract
This invention is directed to the three dimensional crystal structure of Beta-site APP Cleaving Enzyme (BACE), and to the use of this structure in rational drug design methods to identify agents that may interact with active sites of BACE. Such agents may represent new therapeutics in the treatment and/or prevention of Alzheimer's Disease.