The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 08, 2009
Filed:
Oct. 04, 2006
Cindy A. Sprecher, Seattle, WA (US);
Julia E. Novak, Bainbridge Island, WA (US);
James W. West, Seattle, WA (US);
Scott R. Presnell, Tacoma, WA (US);
Richard D. Holly, Seattle, WA (US);
Andrew J. Nelson, Shoreline, WA (US);
Cindy A. Sprecher, Seattle, WA (US);
Julia E. Novak, Bainbridge Island, WA (US);
James W. West, Seattle, WA (US);
Scott R. Presnell, Tacoma, WA (US);
Richard D. Holly, Seattle, WA (US);
Andrew J. Nelson, Shoreline, WA (US);
ZymoGenetics, Inc., Seattle, WA (US);
Abstract
Novel polypeptide combinations, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for soluble zalpha11 receptors that may be used as novel cytokine antagonists, and within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block zalpha11 Ligand activity in vitro and in vivo, and may be used in conjunction with zalpha11 Ligand and other cytokines to selectively stimulate the immune system. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.