The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 08, 2009
Filed:
Mar. 06, 2007
Zbigniew Majka, Lubzina, PL;
Katarzyna Ewa Rusin, Warsaw, PL;
Dominik Daniel Kludkiewicz, Warsawa, PL;
Krzysztof Kurowski, Siedlce, PL;
Katarzyna Joanna Matusiewicz, Lwowek Slaski, PL;
Tomasz Stawinski, Wiazowna, PL;
Daniel Sulikowski, Gubin, PL;
Piotr Kowalczyk, Warsaw, PL;
Zbigniew Majka, Lubzina, PL;
Katarzyna Ewa Rusin, Warsaw, PL;
Dominik Daniel Kludkiewicz, Warsawa, PL;
Krzysztof Kurowski, Siedlce, PL;
Katarzyna Joanna Matusiewicz, Lwowek Slaski, PL;
Tomasz Stawinski, Wiazowna, PL;
Daniel Sulikowski, Gubin, PL;
Piotr Kowalczyk, Warsaw, PL;
Adamed Sp. z o.o., Czosnow K/Warszawy, PL;
Abstract
The invention relates to a method of treatment and/or prophylaxis of diseases and conditions mediated by peroxysome proliferator-activated receptor gamma (PPARγ) in a mammal subject in need thereof, said method comprising administration to said mammal a compound of formula (I) or a pharmaceutically acceptable salt thereof in a therapeutically or prophylactically effective amount wherein in formula (I) W represents a COOH group or its bioisosters, or COO—C-C-alkyl group; Y represents NH or N—C-C-alkyl; Z represents NH, N—C-C-alkyl, N-aryl, N-heteroaryl, S, or O; X represents O, S, NH, N—C-C-alkyl, N-aryl, NSO—C-C-alkyl, N—SO-aryl, or N S0-heteroaryl; Rto Reach independently represents a hydrogen atom or a substituent defined in the description; A is as defined in the description; n represents an integer from 0 to 4, inclusive. The compounds of formula (I) are the ligands of PPAR-gamma receptor.