The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 08, 2009
Filed:
Sep. 30, 2005
Atsushi Naganawa, Mishima-gun, JP;
Tetsuji Saito, Mishima-gun, JP;
Kaoru Kobayashi, Mishima-gun, JP;
Takayuki Maruyama, Mishima-gun, JP;
Yoshihiko Nakai, Mishima-gun, JP;
Shinsuke Hashimoto, Sakai-gun, JP;
Atsushi Naganawa, Mishima-gun, JP;
Tetsuji Saito, Mishima-gun, JP;
Kaoru Kobayashi, Mishima-gun, JP;
Takayuki Maruyama, Mishima-gun, JP;
Yoshihiko Nakai, Mishima-gun, JP;
Shinsuke Hashimoto, Sakai-gun, JP;
Ono Pharmaceuticals Co., Ltd., Osaka, JP;
Abstract
An N-phenylarylsulfonylamide compound of formula (I) (Ris COOH etc.; Ris hydrogen, methyl, etc.; Rand Rare a combination of methyl and methyl, etc.; Ris isopropyl etc.; Ar is thiazolyl, pyridyl, 5-methyl-2-furyl each optionally substituted with methyl; n is zero or 1), a synthetic intermediate for the compound and a process for its preparation. The compound of formula (I) binds to a prostaglandin Ereceptor, especially an EPsubtype receptor, and antagonizes it. It is less affected by protein binding, so it has a satisfactory in vivo activity. Therefore, it is considered to be useful as an analgesic, an antipyretic agent, an agent for the treatment of pollakiuria (frequent urination) and/or lower urinary tract disease syndrome or an antineoplastic agent.