The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 08, 2009
Filed:
Jun. 15, 2007
Panisadee Avirutnan, Bangkok, TH;
Prida Malasit, Bangkok, TH;
Sucharit Bhakdi Punyaratabhandu, Mainz, DE;
Watchara Kasinrerk, Chaing Mai, TH;
Chunya Pauttikhunt, Bangkok, TH;
Panisadee Avirutnan, Bangkok, TH;
Prida Malasit, Bangkok, TH;
Sucharit Bhakdi Punyaratabhandu, Mainz, DE;
Watchara Kasinrerk, Chaing Mai, TH;
Chunya Pauttikhunt, Bangkok, TH;
Mahidol University, Bangkok, TH;
Abstract
The present specification discloses methods of determining risk of developing Dengue Hemorrhagic Fever/Dengue Shock Syndrome (DHF/DSS) in an individual infected with dengue virus (DV). The methods comprise determining, in a fluid or tissue sample of an individual, the presence, absence or quantity of dengue virus protein NS1, and determining, in a fluid or tissue sample of the individual, presence, absence or quantity of SC5b-9 complement complex. The methods can further comprise comparing the levels of NS1 protein and SC5b-9 complement complex with a database comprising epidemiological data correlating levels of NS1 protein and SC5b-9 complement complex with probability of developing DHF/DSS in a population.