The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 01, 2009
Filed:
Jun. 14, 2007
Geoffrey Bodenhausen, Paris, FR;
Paul Vasos, Lausanne, CH;
Riddhiman Sarkar, Prilly, CH;
Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, CH;
Bruker BioSpin AG, Faellanden, CH;
Abstract
A nuclear magnetic resonance (NMR) method for singlet-state exchange NMR-spectroscopy comprises steps of excitation of single-quantum in-phase coherences, generation of single-quantum anti-phase coherences, excitation of zero-quantum coherences ZQand/or longitudinal two-spin order 2IS(='ZZ order') using a π/4 pulse, reversal of the sign of the zero-quantum coherences ZQunder the effect of the difference of the chemical shifts of the examined spins, transformation of the zero-quantum coherences ZQand/or longitudinal two-spin ZZ order into singlet-state populations by means of RF irradiation during a mixing period τ, reconversion of the singlet-state populations remaining at the end of the mixing period τinto zero-quantum coherences ZQand/or ZZ order, reversal of the sign of the zero-quantum coherences ZQunder the effect of the difference of the chemical shifts of the examined spins, and reconversion of zero-quantum coherences ZQand/or ZZ order into single-quantum anti-phase coherences. With the broadband method for the excitation of single state population, NMR can monitor correlations between states that are connected through very slow processes.