The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 01, 2009
Filed:
May. 29, 2007
Richard J. H. Begent, London, GB;
Kerry Ann Chester, London, GB;
Christilyn P. Graff, Cambridge, MA (US);
K. Dane Wittrup, Cambridge, MA (US);
Richard J. H. Begent, London, GB;
Kerry Ann Chester, London, GB;
Christilyn P. Graff, Cambridge, MA (US);
K. Dane Wittrup, Cambridge, MA (US);
Cancer Research Technology Limited, London, GB;
Massachusetts Institute of Technology, Cambridge, MA (US);
Abstract
The present invention relates to improved antibodies against tumor surface antigens and their use in the treatment of tumors. Of particular interest are highly stable, humanized, high affinity antibodies against carcinoembryonic antigen (CEA), especially the antibody we have termed sm3E, which is derived from the scFv antibody MFE-23. Such antibodies have the potential for improved therapeutic efficacy.