The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 01, 2009
Filed:
Jun. 29, 2007
Shigeo Ohta, Hon-machida, Machida-shi, Tokyo, JP;
Sadamitsu Asoh, Kashimada, Saiwai-ku, Kawasaki-shi, Kanagawa, JP;
Shigeo Ohta, Hon-machida, Machida-shi, Tokyo, JP;
Sadamitsu Asoh, Kashimada, Saiwai-ku, Kawasaki-shi, Kanagawa, JP;
Other;
Abstract
The present invention provides an genetically engineered cDNA of the rat bcl-x gene, which has at least one substitution selected from the substitutions that change residues 22 Tyr to Phe, residues 26 Gln to Asn and residues 165 Arg to Lys, in the coding region of rat bcl-x cDNA of SEQ ID NO: 1, a recombinant vector containing the engineered cDNA, a cell into which the recombinant vector was introduced, and an improved protein of Bcl-x. The improved protein of Bcl-xis useful as an ingredient for remedies for various diseases accompanied with cell death since it effectively inhibit cell death such as apoptosis.