The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 01, 2009

Filed:

Jun. 18, 2004
Applicants:

Ganga Raju Gokaraju, Andhra Pradesh, IN;

Rama Raju Gokaraju, Andhra Pradesh, IN;

Venkata Subbaraju Gottumukkala, Andhra Pradesh, IN;

Trimurtulu Golakoti, Andhra Pradesh, IN;

Inventors:

Ganga Raju Gokaraju, Andhra Pradesh, IN;

Rama Raju Gokaraju, Andhra Pradesh, IN;

Venkata Subbaraju Gottumukkala, Andhra Pradesh, IN;

Trimurtulu Golakoti, Andhra Pradesh, IN;

Assignee:

Laila Nutraceuticals, Andhra Pradesh, IN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/21 (2006.01); A61K 31/015 (2006.01); C07C 69/74 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to novel AKBA analogs of the formula I given below: Where in R, R, R, Rand Rin each of the said analogs are: These compounds exhibited 5-Lipoxigenase inhibitory properties and these compounds may be used in pharmaceutical compositions for therapeutic applications against a variety of inflammations and hypersensitivity-based human diseases including asthma, arthritis, bowel diseases such as ulcerative colitis and circulatory disorders such as shock and ischaemia. These compounds also inhibited the growth of Brine Shrimp in cultures, which may be considered as a positive indication for cytotoxicity and antitumor activity.


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