The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 01, 2009

Filed:

May. 26, 2003
Applicants:

Philippe R. Bovy, Mareil Marly, FR;

Roberto Cecchi, Lodi, IT;

Tiziano Croci, Milan, IT;

Olivier Venier, Saint Mande, FR;

Inventors:

Philippe R. Bovy, Mareil Marly, FR;

Roberto Cecchi, Lodi, IT;

Tiziano Croci, Milan, IT;

Olivier Venier, Saint Mande, FR;

Assignee:

sanofi-aventis, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/445 (2006.01); C07D 211/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to the compounds of general formula (I) where Rrepresents H, a (C1-C4)alkyl, —CO(C1-C4)alkyl, (C1-C4)alkylphenyl or —CO-phenyl group, said phenyl being optionally substituted, Rrepresents H, a halogen atom, an —S(O)R, —NHSOR, —NHSO-phenyl or —NHSO—(C1-C4)alkylphenyl group where z is equal to 0, 1 or 2 and where Rrepresents a (C1-C4)alkyl group, said phenyl being optionally substituted; where n is equal to 0, 1 or 2, Rand Rrepresent H, a (C1-C4)alkyl, hydroxyl, cyano, phenyl, benzyl, piperidyl, —CONH, —CO-phenyl, —COOR, —CH(phenyl) (OH) and —C(phenyl)(OH) group, or Rand Rform together an optionally substituted 6-membered aromatic ring, Rrepresents H, a (C1-C4)alkyl, phenyl or benzyl group, and B represents a 5- or 6-membered nitrogen-containing heterocycle or homocycle optionally fused with a phenyl Group or optionally substituted; their addition salts; their method of preparation and their therapeutic application.


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