The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 01, 2009

Filed:

Jun. 18, 2003
Applicants:

Antonio Guarna, Seano, IT;

Federico Cozzolino, Caldine Fiesole, IT;

Maria Torcia, Florence, IT;

Enrico Garaci, Rome, IT;

Inventors:

Antonio Guarna, Seano, IT;

Federico Cozzolino, Caldine Fiesole, IT;

Maria Torcia, Florence, IT;

Enrico Garaci, Rome, IT;

Assignee:

Mimetech S.r.l., Florence, IT;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/535 (2006.01); A01N 43/42 (2006.01); A61K 31/00 (2006.01); A01N 43/00 (2006.01); A01N 43/62 (2006.01); C07D 498/00 (2006.01); C07D 513/00 (2006.01); C07D 515/00 (2006.01); C07D 243/00 (2006.01); C07D 257/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention refers to pharmaceutical preparations including as active compounds 3-aza-bicyclo[3.2.1]octane derivatives of general formula (I) and/or their dimers of general formula (II) and (III) acting as agonists of human neurotrophines. Therefore, such compounds of formula (I), (II) and (III) are useful for treatment of diseases in which the neurotrophine functions are involved in defect, particularly of Nerve Growth Factor (NGF), such as neurodegenerative diseases of central nervous system (CNS), acquired immunodeficiency due to a reduced NGF biodisponibility, or morbous conditions in which the stimulus of neoangiogenesis process is convenient.


Find Patent Forward Citations

Loading…