The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 01, 2009
Filed:
Mar. 28, 2008
Applicants:
David Mark Rotstein, Sunnyvale, CA (US);
Chris Richard Melville, Palo Alto, CA (US);
Inventors:
David Mark Rotstein, Sunnyvale, CA (US);
Chris Richard Melville, Palo Alto, CA (US);
Assignee:
Roche Palo Alto LLC, Palo Alto, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/14 (2006.01); A61K 31/537 (2006.01);
U.S. Cl.
CPC ...
Abstract
This invention relates to piperidine derivatives of formula I wherein R, R, Rand Rare as defined herein useful in the treatment of a variety of disorders, including those in which the modulation of CCR5 receptors is implicated. Disorders that may be treated or prevented by the present derivatives include HIV and genetically related retroviral infections (and the resulting acquired immune deficiency syndrome, AIDS), rheumatoid arthritis, solid organ transplant reject (graft vs. host disease), asthma and COPD.