The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 24, 2009
Filed:
Jan. 09, 2006
Xiaojun Zhang, Furlong, PA (US);
Eldon Scott Priestley, Yardley, PA (US);
Alexandra A. Nirschl, Yardley, PA (US);
Yan Zou, Levittown, PA (US);
Xiaojun Zhang, Furlong, PA (US);
Eldon Scott Priestley, Yardley, PA (US);
Alexandra A. Nirschl, Yardley, PA (US);
Yan Zou, Levittown, PA (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
Abstract
The present invention relates generally to phenylglycinamide derivatives that inhibit serine proteases. In particular it0 is directed to novel phenylglycinamide derivatives, and analogues thereof, which are useful as selective inhibitors of serine protease enzymes of the coagulation cascade; for example thrombin, factor VIIa, factor Xa, factor XIa, factor IXa, and/or plasma kallikrein. In particular, it relates to compounds that are factor VIIa inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of using the same.