The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 24, 2009
Filed:
Jun. 07, 2004
Shigekazu Nagata, Kyoto-fu, JP;
Takashi Suda, Ishikawa, JP;
Tomohiro Takahashi, Tokyo, JP;
Norio Nakamura, Tokyo, JP;
Shigekazu Nagata, Kyoto-fu, JP;
Takashi Suda, Ishikawa, JP;
Tomohiro Takahashi, Tokyo, JP;
Norio Nakamura, Tokyo, JP;
Mochida Pharmaceutical Co., Ltd., Tokyo, JP;
Osaka Bioscience Institute, Osaka-fu, JP;
Abstract
This invention provides a polypeptide useful in the field of medicines, a DNA which encodes the novel polypeptide, a recombinant DNA molecule which contains the DNA, a transformant transformed with the DNA or the recombinant DNA molecule, a process for the purification of the polypeptide, a process for the production of the polypeptide, an antibody which recognizes the polypeptide, an oligonucleotide complementary to the DNA and a screening method. Particularly this invention provides a polypeptide, which is Fas ligand or a fragment thereof. This polypeptide can be used as an effective ingredient of a medicament for regulating the apoptosis in a living body. This polypeptide is obtained by identifying a DNA fragment, which encodes the polypeptide, transforming a desired host with a recombinant DNA molecule, which contains the DNA fragment, and purifying the polypeptide produced by the resulting transformant. This polypeptide has a cytoplasmic domain, a transmembrane domain and extracellular domain and takes part in apoptosis.