The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 24, 2009

Filed:

Aug. 11, 2005
Applicants:

Yan Zhu, Foster City, CA (US);

Jingyuan MA, Fremont, CA (US);

Peng Cheng, Union City, CA (US);

Zuchun Zhao, Pleasanton, CA (US);

Francine M. Gregoire, Lafayette, CA (US);

Vera A. Rakhmanova, Foster City, CA (US);

Inventors:

Yan Zhu, Foster City, CA (US);

Jingyuan Ma, Fremont, CA (US);

Peng Cheng, Union City, CA (US);

Zuchun Zhao, Pleasanton, CA (US);

Francine M. Gregoire, Lafayette, CA (US);

Vera A. Rakhmanova, Foster City, CA (US);

Assignee:

Metabolex Inc., Hayward, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/40 (2006.01); A61K 31/415 (2006.01); C07D 207/00 (2006.01); C07D 231/00 (2006.01); C07D 233/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to certain novel compounds represented by Formula (I) and pharmaceutically acceptable salts, solvates, hydrates and prodrugs thereof. The present invention is also directed to methods of making and using such compounds and pharmaceutical compositions containing such compounds to treat or control a number of diseases mediated by PPAR such as glucose metabolism, lipid metabolism and insulin secretion, specifically Type 2 diabetes, hyperinsulinemia, hyperlipidemia, hyperuricemia, hypercholesteremia, atherosclerosis, one or more risk factors for cardiovascular disease, Syndrome X, hypertriglyceridemia, hyperglycemia, obesity and eating disorders.


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