The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 24, 2009

Filed:

Sep. 21, 2006
Applicants:

C. Frank Bennett, Carlsbad, CA (US);

Susan M. Freier, San Diego, CA (US);

Thomas P. Condon, Singapore, SG;

Inventors:

C. Frank Bennett, Carlsbad, CA (US);

Susan M. Freier, San Diego, CA (US);

Thomas P. Condon, Singapore, SG;

Assignee:

Isis Pharmaceuticals, Inc., Carlsbad, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods for slowing disease progression in an individual suffering from familial ALS are provided. Also provided are methods of increasing the survival time of an individual suffering from familial ALS. These methods employ antisense oligonucleotides targeted to SOD1, for use in inhibiting the expression of SOD1 in the central nervous system of an individual suffering from familial ALS.


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