The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 17, 2009
Filed:
May. 19, 2006
Stefan Abrecht, Duggingen, CH;
Jean-michel Adam, Reinach, CH;
Alec Fettes, Zurich, CH;
Joseph Foricher, Mulhouse, FR;
Bruno Lohri, Reinach, CH;
Patrizio Mattei, Riechen, CH;
Gerard Moine, Riedisheim, FR;
Rudolf Schmid, Basel, CH;
Ulrich Zutter, Basel, CH;
Stefan Abrecht, Duggingen, CH;
Jean-Michel Adam, Reinach, CH;
Alec Fettes, Zurich, CH;
Joseph Foricher, Mulhouse, FR;
Bruno Lohri, Reinach, CH;
Patrizio Mattei, Riechen, CH;
Gerard Moine, Riedisheim, FR;
Rudolf Schmid, Basel, CH;
Ulrich Zutter, Basel, CH;
Hoffman-La Roche Inc., Nutley, NJ (US);
Abstract
This invention relates to a process of the preparation of the novel intermediate (S)-4-fluoromethyl-dihydro-furan-2-one of the formula and with its use for the manufacture of pyrido[2,1-a]isoquinoline derivatives of the formula which are useful for the treatment and/or prophylaxis of diseases which are associated with DPP IV.