The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 17, 2009
Filed:
Sep. 15, 2005
Han-cheng Zhang, Lansdale, PA (US);
Bruce E. Maryanoff, Forest Grove, PA (US);
William J. Hoekstra, Chapel Hill, NC (US);
Kimberly White, North Wales, PA (US);
Han-Cheng Zhang, Lansdale, PA (US);
Bruce E. Maryanoff, Forest Grove, PA (US);
William J. Hoekstra, Chapel Hill, NC (US);
Kimberly White, North Wales, PA (US);
Janssen Pharmaceutica, N.V., , BE;
Abstract
The invention is directed to novel heteroaryl peptidomimetic compounds which are useful as thrombin receptor antagonists for the treatment of diseases associated with thrombosis, restenosis, hypertension, heart failure, arrhythmia, inflammation, angina, stroke, atherosclerosis, ischemic conditions, angiogenesis and related disorders, cancer, and neurodegenerative disorders. Pharmaceutical compositions comprising the substituted heteroaryl peptidomimetics of the present invention and methods of treating conditions mediated by the thrombin receptor are also disclosed.