The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 17, 2009
Filed:
Feb. 08, 2005
Adelheid R. Kuehnle, Honolulu, HI (US);
Adelheid R. Kuehnle, Honolulu, HI (US);
University of Hawaii, Honolulu, HI (US);
Abstract
Disclosed are the uses of inactive gene sites (the pseudogenes) to create a novel selection system and/or targeting sites for mediating the insertion of genetic material into plant and microalgae plastids, for expression of the inserted genetic material under control of the regulatory sequences of a pseudogene. The specific polynucleotides to be used, solely or in any combination thereof, are publicly available from GeneBank. Exemplified is insertion of constructs that contain open reading frames having sequences that upon expression will produce active proteins with the following enzyme activities: (a) acetoacetyl CoA thiolase (EC 2.3.1.9), (b) 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) synthase (EC 4.1.3.5), (c) HMG-CoA reductase (EC 1.1.1.34), (d) mevalonate kinase (EC 2.7.1.36), (e) phosphomevalonate kinase (EC 2.7.4.2), (f) mevalonate diphosphate decarboxylase (EC 4.1.1.33), (g) isopentenyl diphosphate (IPP) isomerase (EC 5.3.3.2), and (h) phytoene synthase (EC 2.5.1.32).